Global Head of Multiple Myeloma Strategy, Hematology, Oncology R&D

Gaithersburg, Maryland

Posted in Pharmaceuticals
about 2 months ago

This job has expired.

Job Info


At AstraZeneca, we win through the science, it's at the heart of our every success. Every decision is rooted in the limitless possibilities of what science can do. We focus our science in the areas of Hematology-Oncology, Respiratory, CVRM and INA.

We push the boundaries of science to deliver life-changing medicines. This purpose underpins everything we do. Itgives us a reason to come to work every day. It reminds us why we exist as a company. It helps us deliver benefits to patients and create value for shareholders. It also sets the context for our employees' activities and the roles of our teams, partners and other collaborators.

AstraZeneca has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.


Hematology is central to our strategy and our vision for AstraZeneca becoming the leading company in the discovery and development of innovative medicines for cancer patients. Building on the success of Acalabrutinib we have created a stand-alone Hematology group within Oncology R&D that leverages our technology platforms and deep mechanistic scientific activities and brings together all hematology projects and activities into a single group, spanning discovery, early and late development.

At AstraZeneca, we are committed to advancing the science of oncology to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of four scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Anti-body-drug Conjugates) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. There are many types of cancer disease. For us to be most effective, we've chosen to concentrate on four key disease areas; Lung Cancer, Breast Cancer, Ovarian Cancer and Hematology.

As the Global Head of Multiple Myeloma Strategy you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biopharmaceutical companies, we're pioneering innovative research and exploring novel pathways using both small and large molecules. The role can be based out of the following sites in the US (Gaithersburg, MD, New York City, Boston and San Francisco) or in Cambridge, UK.

The Global Head of Multiple Myeloma Strategy is a core member of the Hematology R&D Leadership team and will provide scientific, clinical and strategic input into Global Product Teams, Therapeutic Area Strategy and the Oncology Business Unit.

Responsibilities include:

  • Identify unmet medical need areas for developing new therapies in multiple myeloma
  • Guide the development plans for AZ assets in multiple myeloma
  • Identify gaps in portfolio for opportunities for business development or in-house drug development
  • Collaborate with different discovery groups to create a pipeline of new therapeutics for multiple myeloma
  • Guide the development of and the conduct of clinical trials in multiple myeloma
  • Guide preclinical and clinical external collaborations with academic centers and investigators
  • Set up and chair multiple myeloma Scientific Advisory Board Meetings

Essential for the role
  • Qualified Physician (M.D. degree or equivalent), Medical specialty and sub-specialty training and certification in Hematology/oncology required
  • Clinical drug development experience in academic institution or biopharma industry
  • Deep mechanistic pre-clinical and clinical expertise in myeloma and plasma cell dyscrasia. Expert command of the scientific and treatment landscapes for registered and developmental agents in multiple myeloma.
  • Expert knowledge on the patient journey for patients with multiple myeloma, from diagnosis through treatment. Ability to translate that knowledge into strategies to tackle the highest areas of unmet need.
  • Robust knowledge of and evidence of successful hematology product development based on strong scientific and clinical experience
  • Demonstrated understanding of hematology patient selection and stratification including companion/complementary diagnostic development and registration
  • Ability to lead and drive progress in a matrix environment

Desirable for the role
  • Academic, cancer center or industry experience preferred
  • Credible with Key External Hematology Experts, and oncology scientific communities
  • Internationally recognized as an expert in Myeloma and plasma cell dyscrasia.

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