GENERAL SUMMARY/ OVERVIEW STATEMENT:
Katarina Ruscic, M.D., Ph.D, of the Department of Anesthesia, Critical Care and Pain Medicine (DACCPM) at Massachusetts General Hospital (MGH) is seeking a motivated and experienced candidate to join her research project. Our current work seeks to elucidate the molecular and cellular physiology underlying lymphatic vessel contractility using mouse models. The work is performed within the laboratory of Timothy Padera, Ph.D., a leader in lymphatic imaging, tumor growth and lymphatic metastasis and the Edwin Steele Laboratories for Tumor Biology, a world class cancer research group.
To accomplish the overarching goals of this project, the candidate will be expected to complete the following techniques: rodent lymphatic surgery, RNA and protein isolation, qPCR, Western blot, immunohistochemistry (IHC)/immunocytochemistry (ICC), various imaging techniques (intravital microscopy, confocal microscopy, etc.), analysis of raw data in various software programs (MATLAB, GraphPad Prism, Excel and ImageJ) and graphical presentation of results.
This role is suited for an individual looking to pursue an advanced research degree. The candidate will be strongly encouraged to present work in weekly lab meetings and at conferences. Applicants with experience in rodent work are preferred.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position.
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